Dr. John Sadoff, M.D., is a cardiothoracic surgeon at Prairie Cardiovascular – O’Fallon. Dr. Sadoff is a highly skilled surgeon specializing in complex surgeries on the heart and lungs. He provides advanced care for patients with conditions such as coronary artery disease, heart valve disorders, lung cancer, benign diseases of the chest and thoracic aneurysms. At Prairie Cardiovascular, Dr. Sadoff utilizes state-of-the-art technology to perform procedures ranging from minimally invasive surgeries to life-saving interventions, ensuring personalized and high-quality care for every patient. Dr. Sadoff credits a team of professionals that has worked together for decades, with the caring, expert service that has resulted in outcomes that are among the best in the nation.

Dr. Sadoff has received the prestigious Ralph D. Alley Award for cardiac surgery, an honor recognizing outstanding contributions and excellence in the field of cardiovascular care. This award is presented to surgeons who demonstrate exceptional skill, innovation, and commitment to advancing cardiac surgical techniques and improving patient outcomes.

Earning his medical degree from Albany Medical College in Albany, N.Y., Dr. Sadoff completed a general surgery residency at Robert Wood Johnson Medical School (UMDNJ) in New Brunswick, N.J. He performed a cardiothoracic surgery fellowship at the University of North Carolina School of Medicine in Chapel Hill, N.C., where he developed expertise in advanced surgical techniques and patient care. Dr. Sadoff has served our community faithfully for almost 23 years and has deep root in the region.

Dr. Sadoff has published numerous peer-reviewed articles and presented lectures on the role of nitric oxide in managing cardiac failure. He has also advanced surgical practices by developing innovative, less invasive techniques that shorten recovery times and improve patient outcomes.